DIGOXIN AND LEVOTHYROXINE

Hypothyroid subjects are relatively sensitive to the effects of digoxin and so need lower doses. As treatment with levothyroxine progresses, and they become euthyroid, the dosage of digoxin will need to be increased.
Monitor the outcome of resolving hypothyroidism, checking for to ensure that the effects of digoxin are adequate. Monitor digoxin levels as necessary.