DIGOXIN AND HERBAL MEDICINES OR DIETARY SUPPLEMENTS - GINSENG

A man taking digoxin developed grossly elevated serum digoxin levels, without
symptoms of toxicity, while taking Siberian ginseng. Both Chinese ginseng (Panax
ginseng) and Siberian ginseng (Eleutherococcus senticosus) may interfere with some
digoxin assays, including fluorescence polarisation immunoassay (FPIA) and micro-
particle enzyme immunoassay (MEIA).
Whether serum digoxin levels are actually affected is uncertain. Be aware that
ginseng can possibly elevate serum digoxin levels or affect the assay of digoxin.
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