DIAZOXIDE (ORAL)

(DYE az OX ide) Brand: Proglycem

What is the most significant information I must know about oral diazoxide?

• You must not take this medicine if you are allergic to diazoxide or diuretics (water pills). Oral diazoxide must not be used to treat casual hypoglycemia related to diet.

• Till taking diazoxide, speak your doctor if you have congestive heart failure, kidney malady, gout, tall cholesterol, or low potassium.

• Take this medicine exactly as predesigned by your doctor. Do not take it in larger amounts or for longer than recommended. Your doctor may occasionally change your doze to create certain you get the excellent results from this medication.

• If your blood sugar gets too tall (hyperglycemia), you may have symptoms such as heighten thirst, loss of appetite, fruity breath odor, heighten urination, drowsiness, dry skin, nausea, and vomiting. Speak your doctor right away if you have any of these symptoms.

• To be certain this medicine is helping your condition and not causing deleterious effects, your urine will need to be tested often for the presence of glucose (sugar) or ketones. You may be able to do this testing at house. Call your doctor if you have any emergency test result.

• Your doctor may also want you to have blood or urine trials at regular intervals. Do not miss any scheduled appointments.

• Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are taking diazoxide.

• If your condition does not improve after taking diazoxide for 2 to 3 weeks, stop taking the medicine and conversation to your doctor.

What is diazoxide?

Diazoxide given orally raises blood sugar by slowing the release of insulin from the pancreas.

Diazoxide is used to treat low blood sugar (hypoglycemia) related to determined cancers that affect the pancreas and reason it to release too many insulin.

Diazoxide may also be used for purposes another than those listed in this medicine guide.

What must I discuss with my health care provider till receiving diazoxide?

• You must not take this medicine if you are allergic to diazoxide or diuretics (water pills). Oral diazoxide must not be used to treat casual hypoglycemia related to diet.

• Till taking diazoxide, speak your doctor if you are allergic to any drugs, or if you have:

· congestive heart failure;

· kidney disease;

· gout;

· tall cholesterol or triglycerides; or

· low levels of potassium in your blood (hypokalemia).

• If you have any of these conditions, you may need a doze adjustment or particular trials to safely take diazoxide.

• FDA pregnancy category C. This medicine may be deleterious to an unborn child. Speak your doctor if you are pregnant till you take diazoxide.

Diazoxide can pass into breast milk and may harm a nursing child. Do not use this medicine without telling your doctor if you are breast-feeding a baby.

How must I take diazoxide?

• Take this medicine exactly as predesigned by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

• Your doctor may occasionally change your doze to create certain you get the excellent results from this medication.

• Shake the oral suspension (liquid) well just till you measure a doze. To be certain you get the correct doze, measure the liquid with the marked medication dropper provided, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Diazoxide generally begins to work within 1 hour, and its effects can recent up to 8 hours.

• If your blood sugar gets too tall (hyperglycemia), you may have symptoms such as heighten thirst, loss of appetite, fruity breath odor, heighten urination, drowsiness, dry skin, nausea, and vomiting. Speak your doctor right away if you have any of these symptoms.

• To be certain this medicine is helping your condition and not causing deleterious effects, your urine will need to be tested often for the presence of glucose (sugar) or ketones. You may be able to do this testing at house. Call your doctor if you have any emergency test result.

• Your doctor may also want you to have blood or urine trials at regular intervals. Do not miss any scheduled appointments.

• If your condition does not improve after taking diazoxide for 2 to 3 weeks, stop taking the medicine and conversation to your doctor.

• Store diazoxide at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. If it is nearly time for your following doze, wait before then to take the medication and skip the missed doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention if you think you have used too many of this medicine.

• Overdose symptoms may include heighten thirst or urination, fruity breath odor, nausea, and vomiting, or feeling like you might pass out.

What must I avoid while taking diazoxide?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are taking diazoxide.

What are the possible side effects of diazoxide?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· shortness of breath, swelling in your hands or feet;

· rapid pulse;

· quick or pounding heartbeats;

· chest pain;

· blurred vision, eye pain, or seeing halos near lights;

· light bruising or bleeding, unusual weakness;

· fever, chills, body aches, flu symptoms;

· urinating smaller than normal; or

· feeling like you might pass out.

• Smaller serious side effects may include:

· temporary magnify in growth of body hair (especially in women and children;

· nausea, vomiting, stomach pain, loss of appetite;

· diarrhea;

· decreased sense of taste;

· headache, dizziness, anxiety;

· weakness; or

· mild itching or skin rash.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect diazoxide?

• The next drugs can interact with diazoxide. Speak your doctor if you have recently taken any of these:

· a diuretic (water pill);

· chlorpromazine (Thorazine);

· phenytoin (Dilantin);

· a blood thinner such as warfarin (Coumadin); or

· drugs to treat tall blood pressure or a prostate mess, such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin), tamsulosin (Flomax).

• This list is not complete and there may be another drugs that can interact with diazoxide. Speak your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start using a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about diazoxide.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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