Desmopressin (DDAVP, Stimate); Pituitary Hormone; Inj: 4 mcg/mL
Nasal soln, 0.1 mg/mL: 5 mL pump bottle (contains 50 doses of 10 mcg)
Nasal soln, 1.5 mg/mL (Stimate): 2.5 mL pump bottle (contains 25 doses of 150 mcg)
Rhinal tube delivery system: 2.5 mL vial with applicator tubes [0.1 mg/mL]
Tab: 0.1, 0.2 mg;
Diabetes Insipidus:
Oral: <12 yrs: 0.05 mg bid, titrate to desired response, range 0.1-0.8 mg/day; >12 yrs: start with 0.05 mg bid and titrate to response, range 0.1-1.2 mg/day bid-tid
Intranasal: >3 mos-12 yrs: 5 mcg/day q12-24h (range 5-30 mcg/day); >12 yrs: 5-40 mcg/day q8-24h
Must use rhinal tube for doses other than 10 mcg.
IV/SC: 1/10th of the maintenance intranasal dose or if >12 years start with 2-4 mcg/day q12-24h
Titrate dose to achieve
control of excessive thirst and urination.
Hemophilia: >3 mos: 0.3 mcg/kg
IV over 30 minutes
Nocturnal Enuresis: >6 yrs: 20 mcg intranasal qhs (range 10-40 mcg) or 0.2-0.6 mg/day PO qhs
Divide intranasal doses between the two nostrils.