(de ni LOO kin DIF ti tox) Brand: Ontak
• You must not use denileukin diftitox if you have ever had an allergic reaction to a diphtheria vaccine or to medicines containing interleukin-2 (IL-2).
• You may have a reaction from a denileukin diftitox injection within hours or days after receiving the injection. Call your doctor promptly if you have one or more of these symptoms: fever, chills, weakness, muscle or joint pain, nausea, vomiting, or stomach upset.
• Some patients receiving denileukin diftitox have had permanent changes in their vision or capacity to see colors. Conversation with your doctor about your individual risk. Speak your doctor if you have any vision changes during your treatment.
• Denileukin diftitox is a designed protein containing toxins that attach themselves to determined types of malignant cells in the body. Denileukin diftitox works by destroying these malignant cells to slow the progression of cancer.
• Denileukin diftitox is used to treat leukemia and lymphomas, including cutaneous (of the skin) T-cell lymphoma.
• Denileukin diftitox may also be used for purposes not listed in this medicine guide.
• You must not use denileukin diftitox if you have ever had an allergic reaction to a diphtheria vaccine or to medicines containing interleukin-2 (IL-2).
• To create certain denileukin diftitox is safety for you, speak your doctor if you have heart disease.
• Some patients receiving denileukin diftitox have had permanent changes in their vision or capacity to see colors. Conversation with your doctor about your individual risk. Speak your doctor if you have any vision changes during your treatment.
• FDA pregnancy category C. It is not known whether denileukin diftitox will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether denileukin diftitox passes into breast milk or if it could harm a nursing child. Speak your doctor if you are breast-feeding a baby.
• Denileukin diftitox is injected into a vein through an IV. A healthcare provider will give you this injection.
• Denileukin diftitox is generally given every day for 5 days, followed by 3 weeks off the medication.
• While using denileukin diftitox, you may need frequent blood trials at your doctor's office.
• Call your doctor for instructions if you miss an appointment for your denileukin diftitox injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• This medication can pass into body fluids (including urine, feces, vomit, semen, vaginal fluid). For at least 48 hours after you receive a doze, avoid allowing your body fluids to come into contact with your hands or another surfaces. Patients and caregivers must wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands till and after removing gloves. Wash soiled clothing and linens apart from another laundry.
• Body fluids must not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.
• You may have a reaction from a denileukin diftitox injection within hours or days after receiving the injection. Call your doctor promptly if you have one or more of these symptoms: fever, chills, weakness, muscle or joint pain, nausea, vomiting, or stomach upset.
• Call your doctor at once if you have:
· blurred vision, changes in color vision;
· swelling in your hands, ankles, or feet;
· fever, chills, body aches, flu symptoms, sores in your mouth and throat;
· light bruising, unusual bleeding (nose, mouth, vagina, or rectum);
· quick heart rate;
· back pain, trouble breathing or swallowing, chest pain or tightness, tight feeling in your throat;
· a light-headed feeling, like you might pass out; or
· warmth or redness in your person, neck, or chest.
• General side effects may include:
· headache, dizziness, or nervousness;
· numbness or tingling, skin itching or rash;
· runny or stuffy nose;
· weight gain or loss;
· mild diarrhea or constipation; or
· nausea, vomiting, loss of appetite.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Another drugs may interact with denileukin diftitox, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Your doctor or pharmacist can provide more information about denileukin diftitox.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.