Dantrolene sodium (Dantrium); Muscle Relaxant; Cap: 25, 50, 100 mg
Inj: 20 mg;
Spasticity (oral): 1 mg/kg/day bid initially; may increase by 0.5 mg/kg/day q4-7 days to max 3 mg/kg/day bid-qid (max 400 mg/day)
Malignant Hyperthermia prophylaxis: 4-8 mg/kg/day PO q6h given 1-2 days prior to surgery and continued for 3 days after surgery
Malignant Hyperthermia treatment: 1 mg/kg
IV prn, max 10 mg/kg total cumulative dose
Monitor liver function tests