CORTICORELIN OVINE TRIFLUTATE

(KOR ti koe REL in OH vine TRYE floo ate) Brand: Acthrel

What is the most significant information I must know about corticorelin ovine trifluate?

• Speak your doctor about any allergies or medical conditions you have.

• Speak your doctor if you have recently used dexamethasone (Decadron, Dexone, Hexadrol). Dexamethasone can affect the results of your corticorelin test.

• During the corticorelin test, your caregivers will need to draw at least 5 blood samples from you. This will help your doctor determine more about your condition.

• The timing of your blood trials till and after the injection is significant in assuring the most accurate results from a corticorelin test. Plan to remain in the care of your healthcare providers for at least 1 hour after your injection.

• Speak your caregivers at once if you feel like you might pass out, or if you have a quick heart course, a tight feeling in your chest, or if you feel like you need to take deep breaths.

What is corticorelin ovine trifluate?

• Corticorelin ovine trifluate is a man-made form of a hormone that occurs naturally in the body.

• Corticorelin ovine trifluate is used as part of a medical test in people with Cushing's syndrome. Cushing syndrome is an endocrine mess caused by tall levels of cortisol (a steroid hormone produced by the adrenal gland).

• This medicine is also used to help your doctor determine why your body is producing too many of its own cortisol.

• Corticorelin ovine trifluate may also be used for purposes not listed in this medicine guide.

What must I discuss with my health care provider till receiving corticorelin ovine trifluate?

• Speak your doctor about any allergies or medical conditions you have.

• FDA pregnancy category C. This medicine may be deleterious to an unborn child. Till you receive corticorelin ovine trifluate, speak your doctor if you are pregnant.

• It is not known whether corticorelin ovine trifluate passes into breast milk or if it could harm a nursing child. Do not receive this medicine without telling your doctor if you are breast-feeding a baby.

How is corticorelin ovine trifluate given?

• You will receive corticorelin ovine trifluate in a clinic or hospital setting. The medicine is given as a single injection through a needle placed into a vein. Your blood will be tested till and after you receive the injection.

• During the corticorelin test, your caregivers will need to draw at least 5 blood samples from you. This will help your doctor determine more about your condition.

• In most cases, the blood is tested 15 minutes till and then right till you receive the injection. These trials will give your doctor two "baseline" measurements.

• After you receive corticorelin ovine trifluate, your blood will be drawn again at 15 minutes, 30 minutes, and 60 minutes after the injection. This will help your doctor determine more about your condition.

What happens if I miss a dose?

• Since this medicine is generally given as a single doze, you are not likely to be on a dosing schedule.

• The timing of your blood trials till and after the injection is significant in assuring the most accurate results from a corticorelin test. Plan to remain in the care of your healthcare providers for at least 1 hour after your injection.

What happens if I overdose?

• Search abnormal medical attention if you think you have received too many of this medicine.

• Overdose symptoms may include chest tightness, quick heart course, trouble breathing, or severe redness or warmth in your face.

What must I avoid after receiving corticorelin ovine trifluate?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity after you receive this medication.

What are the possible side effects of corticorelin ovine trifluate?

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your person, lips, tongue, or throat.

• Speak your caregivers at once if you feel like you might pass out, or if you have:

· a quick heart rate;

· a tight feeling in your chest; or

· if you feel like you need to take deep breaths.

• Smaller serious side effects may include warmth, redness, or tingly feeling in your person, neck, or chest.

• This is not a complete list of side effects and others may occur. Speak your doctor about any unusual or bothersome side effect. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect corticorelin ovine trifluate?

• Speak your doctor if you have recently used dexamethasone (Decadron, Dexone, Hexadrol). Dexamethasone can affect the results of your corticorelin test.

• There may be another drugs that can interact with corticorelin ovine trifluate. Speak your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal commodity, and drugs predesigned by another doctors. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about corticorelin ovine trifluate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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