CLOPIDOGREL AND LOW-MOLECULAR-WEIGHT HEPARINS

The manufacturers of clopidogrel note that in various large clinical studies in patients with acute coronary syndrome or myocardial infarction, most patients received LMWHs without an obvious difference in the rate of bleeding or the incidence of major bleeding. However, case reports describe occasional serious bleeding events in those given clopidogrel with a LMWH.
Although concurrent use can be beneficial the manufacturers advise caution because of the possible risk of increased bleeding.
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