CLONIDINE AND METHYLPHENIDATE

There have been fears about serious adverse events when methylphenidate is taken with clonidine due to reports of 3 deaths in children taking both drugs, and because of the theoretical potential for adverse effects such as significant hypertension and/or tachycardia or hypotension and/or bradycardia. Although, studies have failed to establish any link between the use of methylphenidate with clonidine and the reported deaths, adverse effects have been described. Nevertheless, studies have suggested that the combination is both safe and effective for the treatment of attention deficit hyperactivity disorder.
No action needed, although be aware that, rarely, adverse cardiac events may occur.