Clonazepam (Klonopin)
C-IV; Benzodiazepine; Tab: 0.5, 1, 2 mg; <10 yrs or < 30 kg: 0.01-0.03 mg/kg/day PO bid-tid, increase by no more than 0.5 mg/day q3days until
seizures are controlled or adverse effects seen; usual maintenance dose 0.1-0.2 mg/kg/day tid
>10 yrs
AND >30 kg: 0.5 mg PO tid, increase by 0.5-1mg/day q3days until seizures are controlled or adverse effects seen; usual maintenance 0.05-0.2
mg/kg/day
Tablets may be broken in half or quarters.
Therapeutic Serum Level: 20-80 ng/mL
Potentiates
CNS depressant effects of other drugs. Extemporaneously prepared solution may be made from the crushed tablets with 60- day stability
under refrigeration.