CLOMIPHENE

(KLOE mih feen) Brand: Clomid, Serophene

What is the most significant information I must know about clomiphene?

• Use caution when driving, operating machinery, or performing another hazardous activities. Clomiphene may reason blurred vision or another visual side effects during or shortly after therapy. Notify your doctor immediately if you develop any visual side effects and use caution when performing hazardous activities, especially under conditions of variable lighting.

• Clomiphene may magnify the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.

What is clomiphene?

• Clomiphene stimulates the release of hormones necessary for ovulation to occur.

• Clomiphene is used to stimulate ovulation (the release of an egg) when a woman's ovaries can manufacture a follicle but hormonal stimulation is deficient.

• Clomiphene may also be used for purposes another than those listed in this medicine guide.

Who must not take clomiphene?

• Do not take clomiphene without first talking to your doctor if you

· might be pregnant;

· have a thyroid problem or other endocrine disorder;

· have undiagnosed vaginal bleeding;

· have endometriosis or endometrial carcinoma;

· have uterine fibroids;

· have liver disease;

· have ovarian cysts or ovarian enlargement not due to polycystic ovarian syndrome; or

· have any another serious or chronic medical illness.

• You may not be able to take clomiphene, or you may require a lower doze or particular monitoring if you have any of the conditions listed above.

• Do not take clomiphene if you are pregnant. Clomiphene is in the FDA pregnancy category X. This means that it is known to reason birth defects.

• It is not known whether clomiphene pass into breast milk. Do not take clomiphene without first talking to your doctor if you are breast-feeding a baby.

How must I take clomiphene?

• Use clomiphene exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

• Take every doze with a full glass of water.

• Clomiphene is generally taken in 5 day cycles. Follow your doctor's instructions.

• Store clomiphene at room temperature, away from direct easy, moisture, and heat.

What happens if I miss a dose?

• Contact your doctor if you miss a doze of clomiphene.

What happens if I overdose?

• Search abnormal medical attention.

• Symptoms of a clomiphene overdose include nausea, vomiting, flushing, blurred vision, visual spots or flashes, and abdominal pain.

What must I avoid while taking clomiphene?

What are the possible side effects of clomiphene?

• Stop taking clomiphene and search abnormal medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or person; or hives).

• The ovarian hyperstimulation syndrome (OHSS) has been reported to occur in patients receiving clomiphene. Symptoms of OHSS include swelling of the hands or legs, abdominal pain and swelling, shortness of breath, weight gain, and nausea or vomiting. OHSS can be fatal. Notify your doctor immediately or search abnormal medical attention if you develop any of these side effects.

• Another side effects may also occur. Notify your doctor if you experience

· ovarian enlargement presenting as abdominal or pelvic pain, tenderness, pressure, or swelling;

· flushing;

· nausea, vomiting, or diarrhea;

· breast tenderness or discomfort;

· blurred vision or another visual disturbances;

· headache; or

· emergency uterine bleeding.

• Clomiphene may magnify the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.

• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect clomiphene?

• There are no known interactions between clomiphene and another medicines. Conversation to your doctor and pharmacist till taking any prescription or over-the-counter medicines.

Where can I get more information?

• Your pharmacist has additional information about clomiphene written for health professionals that you may read.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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