Ciprofloxacin (Cipro, Ciloxan); Antibacterial, Quinolone; Inj: 200, 400 mg
Ophth oint: 0.3% [3.5 gm[
Ophth soln: 3 mg/mL [2.5, 5, 10 mL]
Susp per 5 mL: 50, 100 mg
Tab: 100, 250, 500, 750 mg;
PO: 20-30 mg/kg/day bid, may use 40 mg/kg/day bid in cystic fibrosis (max 1500 mg/day)
IV: 20-30 mg/kg/day bid, max 800 mg/day; in cystic fibrosis use 30 mg/kg/day, max 1200 mg/day
Anthrax Treatment:
20-30 mg/kg/day
IV q12h x 60 days, max 1000 mg/day; substitute oral for
intravenous (same dose) as soon as
clinical condition improves
Anthrax Post-exposure Prophylaxis:
20 mg/kg/day PO q12h x 60 days, max 1000 mg/day
Ophth: Instill 1-2 drops in affected eye(s) q2h while awake for 2 days then 1-2 drops q4h while awake for 5 more days OR apply ointment tid x 2 days
then bid x 5 days
Not recommended for use in <18 years because of risk of arthropathy unless benefit outweighs risk. Reduce dosage in
renal impairment.