CICLOSPORIN (CYCLOSPORINE) AND SULFONAMIDES

In isolated cases sulfadiazine given orally or sulfadimidine with trimethoprim given intravenously have caused a fall in serum ciclosporin levels. Sulfametoxydiazine possibly caused a minor fall in one case.
These interactions are not firmly established. Until more information is available it would be prudent to check ciclosporin levels if any sulphonamide is added to established treatment with ciclosporin.
(18)
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