Chloramphenicol (Chloromycetin); Antibacterial; Cap: 250 mg
Inj: 1 gm;
Meningitis: 75-100 mg/kg/day IV/PO q6h (max 4 gm/day)
Other infections: 50-75 mg/kg/day IV/PO q6-8h (max 4gm/day)
Therapeutic Serum Levels: Peak 10-20 mcg/mL; trough 5-10 mcg/mL.
Not recommended for neonates because of risk of "gray baby
syndrome." Not a first-line agent due to risk of aplastic
anemia and
bone marrow suppression.