CARBAMAZEPINE AND VACCINES

Carbamazepine levels rose modestly 14 days after influenza vaccination in one study. A case report describes carbamazepine toxicity and markedly increased carbamazepine levels in a teenager 13 days after influenza vaccination.
The moderate increase in serum carbamazepine levels seen in the study is unlikely to have much clinical relevance. However, the case report of markedly increased carbamazepine levels introduces a note of caution. Carbamazepine toxicity may present as nausea, vomiting, ataxia or drowsiness.