A single case report describes a moderate rise in serumcarbamazepine levels in a patient given trazodone. Carbamazepine may moderately decrease trazodone levels. Monitor trazodoneefficacy and increase the dose as needed. The clinical significance of the rise in carbamazepine levels is likely to be small. Indicators of carbamazepinetoxicity include nausea, vomiting, ataxia, drowsiness.
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