Captopril (Capoten); Angiotensin Converting
Enzyme Inhibitor; Tab: 12.5, 25, 50, 100 mg; All doses are PO
Neonates: 0.05-0.1 mg/kg/day PO q8-24h
Infants: Initially 0.15-0.3 mg/kg/dose, titrate dose upward to max of 6 mg/kg/day q6-24h
Children: Initially 0.3-0.5 mg/kg/dose (max 12.5-25 mg), titrate dose upward to max of 6 mg/kg/day q6-24h
Adolescents: Initially 12.5-25 mg q8-12h, titrate dose upward by 25 mg/dose to max of 450 mg/day.
Extemporaneous suspension can be made with 30-day stability under refrigeration. Caution in
renal failure. Can cause rash, proteinuria, persistent
cough.