CALCIUM-CHANNEL BLOCKERS AND CARBAMAZEPINE - OTHER CALCIUM-CHANNEL BLOCKERS

Felodipine, nifedipine and nilvadipine levels are decreased by carbamazepine. All calcium-channel blockers are metabolised by CYP3A4, and carbamazepine would therefore be expected to decrease their levels to some extent.
Monitor the outcome of concurrent use, being aware that the dose of the calcium- channel blocker may need to be raised.
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