A patient taking
buspirone developed marked
CNS adverse effects after starting to take herbal medicines including
St John's wort (Hypericum perforatum), melatonin and Ginkgo biloba. The
serotonin syndrome, has been reported in a patient who
took
buspirone with
St John's wort (Hypericum perforatum).
The general significance of these cases is unclear, but they highlight the importance of considering the adverse effects of herbal medicines when they are used with conventional medicines.