BUPROPION AND PROTEASE INHIBITORS

Ritonavir, both at boosted doses and higher doses, decreases bupropion levels, and reduced efficacy might be expected. This is the opposite effect to that which was originally predicted.
The extent of reduction in bupropion levels seen suggests that the dose of bupropion might need to be doubled. It would seem prudent to start bupropion at the recommended starting dose and titrate to effect. Nevertheless, because of the original in vitro data, the UK manufacturers of bupropion currently caution that the recommended doses should not be exceeded.
(20)
This site is intended for general information only. The information provided on this site does not constitute medical advice and should not be relied upon. You should not act or refrain from acting on any legal or medical matter based on the content of this site.
© 2006-2025 medpill.info Last Updated On: 06/05/2025 (0)
×
Wait 20 seconds...!!!