(bri MON i deen and brin ZOE la mide off THAL mik) Brand: Simbrinza
• Brimonidine and brinzolamide ophthalmic must not be given to a baby younger than 2 years old.
• Brimonidine and brinzolamide ophthalmic reduces the amount of fluid in the eye, which decreases pressure internal the eye.
• Brimonidine and brinzolamide ophthalmic (for the eyes) is a combination medication used to treat open-angle glaucoma or ocular hypertension (high pressure internal the eye).
• Brimonidine and brinzolamide ophthalmic may also be used for purposes not listed in this medicine guide.
• You must not use this medication if you are allergic to brimonidine or brinzolamide.
• Brimonidine and brinzolamide ophthalmic must not be given to a baby younger than 2 years old.
• To create certain brimonidine and brinzolamide ophthalmic is safety for you, speak your doctor if you have:
· kidney disease;
· liver disease;
· congestive heart failure, coronary artery malady, history of stroke or blood clot;
· tall or low blood pressure;
· circulation problems, such as Raynaud's syndrome (numbness or cool feeling in your fingers or toes);
· depression;
· an allergy to sulfa drugs; or
· narrow-angle glaucoma.
• FDA pregnancy category C. It is not known whether brimonidine and brinzolamide ophthalmic will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• It is not known whether brimonidine and brinzolamide ophthalmic passes into breast milk or if it could harm a nursing child. You must not breast-feed while using this medicine.
• Follow all directions on your prescription label. Do not use this medication in larger or less amounts or for longer than recommended.
• Do not use this medicine while wearing contact lenses. Brimonidine and brinzolamide ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medication till putting in your contact lenses.
• Wash your hands till using the eye drops.
• Shake the eye drops well just till every use.
• To apply the eye drops:
· Tilt your head back slightly and pull down your lower eyelid to make a little pocket. Keep the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
· Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the internal corner of the eye for about 1 minute, to hold the liquid from draining into your tear duct.
· Use only the number of drops your doctor has predesigned. If you use more than one drop, wait about 5 minutes between drops.
· Wait at least 5 minutes till using any another eye drops your doctor has prescribed.
• Do not touch the tip of the eye dropper or seat it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.
• Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.
• Speak your doctor right away if you have any eye injury or infection, or if you need to have any type of surgery, especially eye surgery.
• Store at room temperature away from moisture and heat. Do not freeze. Hold the bottle tightly closed when not in use.
• Use the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not use extra medication to create up the missed dose.
• An overdose of brimonidine and brinzolamide ophthalmic is not expected to be dangerous. Search abnormal medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.
• This medicine may reason blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• You may have another signs of allergic reaction that develop more slowly while using this medication. Call your doctor if you have:
· sudden liver failure--nausea, vomiting, itching, weary feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), confusion, rapid weight gain, (especially in your midsection);
· bone marrow suppression--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing, pale skin, feeling light-headed or short of breath, rapid heart course, trouble concentrating; or
· severe skin reaction--fever, sore throat, swelling in your person or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the person or upper body) and causes blistering and peeling.
• Stop using this medication and call your doctor at once if you have:
· blurred vision, tunnel vision, eye pain, or seeing halos near lights; or
· eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection).
• General side effects may include:
· blurred vision;
· mild itching, redness, or irritation of your eyes; or
· dry mouth, unpleasant taste.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Another drugs may interact with brimonidine and brinzolamide ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Your pharmacist can provide more information about brimonidine and brinzolamide ophthalmic.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.