(bev a CIZ oo mab) Brand: Avastin
• Bevacizumab can create it easier for you to bleed. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop. You may also have bleeding on the internal of your body, such as in your stomach or intestines, or in your brain.
• Call your doctor at once if you have: signs of bleeding in your digestive tract-- feeling very weak or dizzy, severe stomach pain, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds; or signs of bleeding in the brain--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance.
• Bevacizumab must not be used within 28 days till or after a planned surgery.
• Bevacizumab can also reason problems with wound healing, which could result in bleeding or infection. Call your doctor if you have signs of any skin infection (sudden redness, warmth, swelling, or oozing), or any skin wound or surgical incision that will not heal.
• Bevacizumab is a cancer medicine that interferes with the growth and spread of cancer cells in the body.
• Bevacizumab is used to treat a determined type of brain tumor, and determined types of cancers of the kidney, lung, colon and rectum. It is generally given as part of a combination of cancer medicines.
• Bevacizumab may also be used for purposes not listed in this medicine guide.
• You must not use bevacizumab if you are allergic to it, or:
· if you have slow healing of a skin wound or surgical incision;
· if you have had surgery within the past 4 weeks (28 days);
· if you have recently been coughing up blood; or
· if you plan to have surgery within the following 4 weeks (28 days).
• To create certain bevacizumab is safety for you, speak your doctor if you have:
· heart malady, tall blood pressure;
· a history of heart onslaught, stroke, or blood clots;
· a bleeding or blood-clotting mess; or
· a history of stomach or intestinal bleeding, or perforation (a hole or tear) in your esophagus, stomach, or intestines.
• FDA pregnancy category C. It is not known whether bevacizumab will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.
• Bevacizumab may reason a woman's ovaries to stop working correctly. Symptoms of ovarian failure include 3 or more missed menstrual periods in a row. This may affect your fertility (ability to have children). Conversation to your doctor about your specific risks.
• It is not known whether bevacizumab passes into breast milk or if it could harm a nursing child. You must not breast-feed while you are being treated with bevacizumab.
• Older adults may be more likely to have side effects from this medication.
• Bevacizumab is injected into a vein through an IV. A healthcare provider will give you this injection.
• Bevacizumab is generally given once each 2 weeks.
• Bevacizumab can reason problems with wound healing, which could result in bleeding or infection. If you need to have any type of surgery, you will need to stop receiving bevacizumab at least 4 weeks onward of time. Do not start using bevacizumab for at least 4 weeks after surgery, or before your surgical incision heals.
• To be certain this medicine is not causing deleterious effects, your blood pressure will need to be checked often. Protein levels in your urine may also need to be tested.
• Bevacizumab should be stored in a refrigerator and kept from freezing. Bevacizumab bottles must never be shaken.
• Call your doctor for instructions if you miss an appointment for your bevacizumab injection.
• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.
• Avoid activities that may magnify your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.
• Bevacizumab can reason a rare but serious neurologic mess affecting the brain. Call your doctor at once if you have a headache, confusion, vision problems, feeling very weak or weary, fainting, or seizure (blackout or convulsions). These rare symptoms may occur within hours of your first doze of bevacizumab, or they may not appear for up to a year after your treatment started.
• Some people receiving bevacizumab have developed a fistula (an emergency passageway) within throat, lungs, gallbladder, kidney, bladder, or vagina. Call your doctor if you have: chest pain and trouble breathing, stomach pain or swelling, urine leakage, or if you feel like you are choking and gagging when you ate or drink.
• Bevacizumab can create it easier for you to bleed. Contact your doctor or search abnormal medical attention if you have bleeding that will not stop. You may also have bleeding on the internal of your body, such as in your stomach or intestines, or in your brain.
• Call your doctor at once if you have:
· signs of bleeding in your digestive tract--severe stomach pain, black or bloody stools, or if you cough up blood or vomit that looks like coffee grounds;
· signs of bleeding in the brain--sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, or problems with vision or balance;
· signs of any skin infection--sudden redness, warmth, swelling, or oozing, or any skin wound or surgical incision that will not heal;
· light bruising, unusual bleeding (nose, mouth, vagina, rectum), purple or red pinpoint spots under your skin, or any bleeding that will not stop;
· fever, vomiting, and constipation;
· swollen gums, painful mouth sores, pain when swallowing, skin sores, cool or flu symptoms, cough;
· pain, swelling, warmth, or redness in one or both legs;
· chest tightness or hard feeling, pain spreading to the jaw or shoulder, nausea, sweating, common ill feeling;
· missed menstrual periods; or
· dangerously tall blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, shortness of breath, uneven heartbeats).
• Some people receiving a bevacizumab injection have had a reaction to the infusion (when the medication is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have a headache, wheezing, or chest pain during the injection.
• General serious side effects may include:
· mild or casual headache;
· runny nose, sneezing;
· dry or watery eyes;
· dry or flaky skin, hair loss;
· changes in your sense of taste; or
· back pain.
• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.
• Another drugs may interact with bevacizumab, including prescription and over-the-counter medicines, vitamins, and herbal commodity. Speak every of your health care providers about all medicines you use now and any medication you start or stop using.
• Your doctor or pharmacist can provide more information about bevacizumab.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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