BETA BLOCKERS AND CLONIDINE

The use of clonidine with beta blockers can be therapeutically valuable, but a sharp and serious rise in blood pressure, rebound hypertension', can follow the sudden withdrawal of clonidine, which may be worsened by the presence of a beta blocker. Note that additive hypotensive effects are likely, see antihypertensives.
Control this adverse effect by stopping the beta blocker several days before starting a gradual withdrawal of clonidine. A successful alternative is to replace the clonidine and the beta blocker with labetalol. The patient may experience tremor, nausea, apprehension and palpitations, but no serious blood pressure rise or headaches occur. If a hypertensive episode develops, control it with phentola- mine. Re-introduction of oral or intravenous clonidine should also stabilise the situation. It is clearly important to emphasise to patients taking clonidine and beta blockers that they must keep taking both drugs.
(22)
© 2006-2024 medpill.info Last Updated On: 03/18/2024 (0)
×
Wait 20 seconds...!!!