Classifications: antitussive; Therapeutic: antitussive; cough suppressant
Pregnancy Category: C
100 mg capsules
Nonnarcotic antitussive activity reported to be somewhat less effective than that of codeine. Does not inhibit respiratory
center at recommended doses.
Decreases frequency and intensity of nonproductive cough.
Decreases frequency and intensity of nonproductive cough in acute and chronic respiratory conditions. Also used in bronchoscopy,
thoracentesis, and other procedures when coughing must be avoided.
Pregnancy (category C), children <10 y.
Route & Dosage
Adult/Child (>10 y): PO 100 mg t.i.d. prn up to 600 mg/d
- Ensure that soft capsules called perles are swallowed whole.
- Store in airtight containers protected from light.
Adverse Effects (≥1%)Body as a Whole:
Drowsiness, sedation headache, mild dizziness. GI: Constipation
, nausea. Skin:
1520 min. Duration:
Assessment & Drug Effects
- Auscultate lungs anteriorly and posteriorly at scheduled intervals.
- Observe character and frequency of coughing and volume and quality of sputum. Keep physician informed.
Patient & Family Education
- Do not chew or allow perle to dissolve in mouth; swallow whole. If perle dissolves in mouth, the mouth, tongue, and pharynx
will be anesthetized. Also, it is unpleasant to taste.