Isolated cases of adverse reactions (chorea, severe headache, facial flushing, massive oedema, and prolonged coma) attributed to interactions between phenelzine and chlordiazepoxide,
clonazepam or nitrazepam, and between
isocarboxazid and chlordiazepoxide have been described.
The case reports of adverse interactions appear to be isolated, and it is by no means certain that all the responses were in fact due to drug interactions.