BALSALAZIDE (bal-sal'a-zide) Colazal Classifications: mucous membrane agent; antiinflammatory agent; Therapeutic: antiinflammatory agent Prototype: Mesalamine (5-ASA) Pregnancy Category: B |
750 mg capsules
A prodrug of mesalamine that remains intact until it reaches the lumen of the colon. Thought to decrease inflammation of the mucous lining of the colon by blocking cyclooxygenase and inhibiting prostaglandin synthesis in the lining of the colon.
An antiinflammatory agent and a prodrug of 5-ASA.
Treatment of mild to moderate active ulcerative colitis.
Prior hypersensitivity to salicylates, balsalazide.
Hypersensitivity to mesalamine, sulfasalazine, olsalazine, salicylate. Allergic response to any medications; hepatic or renal impairment; pregnancy (category B), lactation; pyloric stenosis. Safety and efficacy in children are not established.
Ulcerative Colitis Adult: PO 2250 mg (3 times 750 mg) t.i.d. for 812 wk |
Assessment & Drug Effects
Patient & Family Education