AZOLES AND REBOXETINE

Ketoconazole decreases the clearance of reboxetine, without apparently altering its adverse effect profile. Other azoles are predicted to interact similarly.
It has been suggested that caution should be used, and a reduction in reboxetine dosage considered, if it is given with ketoconazole. The manufacturers recommend that azoles should not be given with reboxetine as it has a narrow therapeutic index, but this seems overly cautious.
(17)
This site is intended for general information only. The information provided on this site does not constitute medical advice and should not be relied upon. You should not act or refrain from acting on any legal or medical matter based on the content of this site.
© 2006-2025 medpill.info Last Updated On: 06/12/2025 (0)
×
Wait 20 seconds...!!!