Taking
atovaquone (tablets or suspension) with fatty food markedly increases its AUC by 2- to 3-fold.
Atovaquone/proguanil tablets should be taken with food or an enteral supple- ment, and
atovaquone suspension should be taken with food. Monitor patients who are unable to tolerate taking
atovaquone with food for treatment failure; consider
intravenous treatment in the case of Pneumocystis
pneumonia.