can apparently lower serum clozapine
levels. The combination of olanzapine
appears to increase the risk of hepatic
injury in children.
Monitor the levels of clozapine
and adjust the dose as necessary. With olanzapine
, it has been suggested that liver enzymes should be monitored every 3 to 4 months for the first year of treatment, thereafter monitoring every 6 months if no adverse effects are detected.