ANTIPSYCHOTICS AND ANTIPSYCHOTICS - CLOZAPINE

The concurrent use of clozapine and risperidone can be effective and well tolerated but isolated reports describe a rise in serum clozapine levels when risperidone was added, and another describes the development of atrial ectopics. Dystonia has been seen when clozapine was replaced by risperidone.
The raised clozapine levels and other adverse reactions seem to be isolated cases and therefore of doubtful general significance.
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