Additive antimuscarinic effects can develop if two or more drugs with antimuscarinic effects are used together. The easily recognised and common peripheral antimuscari- nic effects are blurred vision, dry mouth, constipation, difficulty in urination, reduced sweating and tachycardia. Central effects include confusion, disorientation, visual hallucinations, agitation, irritability, delirium, memory problems, belligerence and even aggressiveness. Problems are most likely to arise in patients with particular
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