Isolated reports describe delayed hallucinations in a patient taking phenelzine and cyproheptadine, and the rapid re-emergence of depression
was given to two other patients taking brofaromine or phenelzine.
It would be prudent to monitor for a reduction in efficacy
or an adverse response if cyproheptadine
is given with any MAOI or RIMA. The manufacturer of cyproheptadine
contraindicates concurrent use with MAOIs
, however, there appears to be no reason why cyproheptadine
cannot be used to treat serotonin syndrome
occurring in a patient taking an MAOI.