ANTIHISTAMINES AND H2-RECEPTOR ANTAGONISTS

Cimetidine moderately raises hydroxyzine levels and considerably raises loratadine levels, but this is not thought to be of clinical significance. The manufacturer of mizolastine recommends caution if cimetidine is taken concurrently because it might increase mizolastine levels and prolong the QT interval. This is a cautious approach since a link between mizolastine and cardiac arrhythmias has not been proven.
No action needed.
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