ANTIHISTAMINES AND BETAHISTINE

A single report describes the re-emergence of labyrinthine symptoms in a patient taking betahistine with terfenadine. This interaction had been predicted on theor- etical grounds because betahistine is an analogue of histamine. Betahistine may therefore oppose the effects of all antihistamines.
The use of antihistamines should be carefully considered in patients taking betahistine.
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