ANTIDIABETICS AND WARFARIN AND OTHER ORAL ANTICOAGULANTS

Although isolated cases of interactions (raised prothrombin times, bleeding or hypoglycaemia) have been seen in patients taking anticoagulants and acarbose, metformin or sulphonylureas, in general no important interaction appears to occur. A decrease in prothrombin time has also been seen with acarbose or metformin.
The isolated cases of bleeding are not expected to represent a general interaction. No interaction has been seen between the oral anticoagulants and miglitol, nateglinide, pioglitazone, repaglinide, rosiglitazone, or voglibose.
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