ANTIDIABETICS AND NICOTINIC ACID (NIACIN)

Nicotinic acid causes deterioration in glucose tolerance, which may be dose-related, and can result in the need for dose adjustment of a patient's antidiabetic drugs. Nevertheless, its beneficial effects on lipids may outweigh its effects on glucose tolerance in some diabetics.
Diabetic control should be closely monitored, recognising that some adjustment of the antidiabetic drugs may be needed.
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