ANTIDIABETICS AND CORTICOSTEROIDS

Corticosteroids with glucocorticoid (hyperglycaemic) activity oppose the blood glucose lowering effects of the antidiabetics. Significant hyperglycaemia has been seen with systemic corticosteroids, and in cases with inhaled corticosteroids or high- potency topical corticosteroids.
It would seem prudent to increase blood glucose monitoring when a corticosteroid is started and adjust the antidiabetic treatment accordingly. Routine monitoring of local corticosteroids appears over-cautious, but be aware that isolated cases of hyperglycaemia have been reported.
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