A
Clonidine may possibly suppress the signs and
symptoms of hypoglycaemia in
diabetics. Marked hyperglycaemia occurred in a child using insulin when
clonidine was given. However, the effect of
clonidine on carbohydrate
metabolism appears to be variable, as other reports have described both increases and decreases in blood glucose levels.
Warn all patients that some of the normal premonitory signs of hypoglycaemia may not appear. Suspect an interaction if disturbances in the
control of
diabetes occur in patients given
clonidine.