A
Itraconazole appears not to affect diabetic
control in most patients, but there are
occasional reports of hypoglycaemia or hyperglycaemia associated with its use.
Itraconazole caused modest increases in
repaglinide and
nateglinide levels, but without affecting the
control of blood glucose levels.
Itraconazole has no effect on pioglitazone
pharmacokinetics.
No action is normally needed but warn patients to report any unexpected changes in blood glucose levels.