An aluminium/magnesium hydroxide antacid given with or 2 hours after gabapentin
reduced its bioavailability by about 20%. When the antacid was given 2 hours before gabapentin
, the bioavailability was reduced by about 10%.
These small changes are unlikely to be of clinical
importance. However, the manufacturer recommends that gabapentin
is taken about 2 hours after alumin- ium/magnesium-containing antacids