Aluminium/magnesium hydroxide has been shown to reduce the bioavailability of cefpodoxime proxetil by about 40%. Sodium bicarbonate and aluminium hydroxide seem to have similar effects.
It has been recommended that cefpodoxime is given at least 2 hours apart from antacids.
Other cephalosporins
Aluminium/magnesium hydroxide reduced the AUC of a modified-release preparation of cefaclor by 18%, but this reduction is small and considered unlikely to be clinically important.
No action needed.
© 2006-2023 Last Updated On: 01/28/2023 (0)
Wait 20 seconds...!!!