Hypothyroidism developed very rapidly in 2 patients taking
amiodarone when
lithium was started.
Note that
lithium has been tried for the treatment of amiodarone-induced hyperthyroidism, and regular monitoring of
thyroid status is recommended throughout
amiodarone treatment.
Lithium therapy has rarely been associated with QT prolongation, and consequently the UK manufacturer of
amiodarone contraindicates its combined use for a general discussion of QT prolongation.