AMINOGLUTETHIMIDE AND THEOPHYLLINE

Aminoglutethimide increases theophylline clearance by almost 50% in some patients, but it is not known whether this results in a clinically relevant decrease in the effects of theophylline. Aminophylline would be expected to be similarly affected.
Monitor the effects and, if necessary, take theophylline levels. Increase the theophylline dosage accordingly.
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