Symptoms of schizophrenia occurred in one patient, and restlessness, agitation and hyperventilation occurred in another, after they took amfetamine with fluoxetine. A patient developed serotonin syndrome, when taking citalopram with dexamfetamine. Similar reactions have also been seen with ecstasy.
The clinical significance of this interaction is unknown, but bear it in mind in case of an unexpected response to treatment.
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