Symptoms of schizophrenia occurred in one patient, and restlessness, agitation and hyperventilation occurred in another, after they took
amfetamine with fluoxetine. A patient developed
serotonin syndrome, when taking citalopram with dexamfetamine. Similar reactions have also been seen with ecstasy.
The
clinical significance of this interaction is unknown, but bear it in mind in case of an unexpected response to treatment.