ALPHA BLOCKERS AND MAOIS

Indoramin


The concurrent use of MAOIs is contraindicated by the manufacturers of indoramin based on a theoretical suggestion that the effects of noradrenaline (norepinephrine) may be potentiated. However, the pharmacology of these drugs suggests just the opposite, namely that hypotension is the more likely outcome. The manufacturers are not aware of any reported interactions between indoramin and MAOIs.
No action needed, but be aware that hypotension is a possibility.
Other Alpha blockers Both MAOIs and alpha blockers have hypotensive effects, which may be additive.
No action needed, but be aware that hypotension is a possibility if any alpha blocker is given with an MAOI.
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