ALPHA BLOCKERS AND DIGOXIN

A 60% rise in digoxin levels occurred over 3 days in one study when prazosin was also given. Clinical experience suggests this interaction is rare.
No action is usually need when prazosin is given with digoxin, although consider an interaction if adverse effects, such as bradycardia occur. Alfuzosin, doxazosin, tamsulosin and terazosin appear not to interact with digoxin.
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