A 60% rise in
digoxin levels occurred over 3 days in one study when prazosin was also given.
Clinical experience suggests this interaction is rare.
No action is usually need when prazosin is given with
digoxin, although consider an interaction if adverse effects, such as bradycardia occur. Alfuzosin, doxazosin, tamsulosin and
terazosin appear not to interact with
digoxin.