ALGLUCOSIDASE ALFA (INJECTION)

(AL gloo KOE si dase AL fa) Brand: Lumizyme, Myozyme

What is the most significant information I must know about alglucosidase alfa?

Alglucosidase alfa is accessible only under a particular program called ACE. Under this program, only registered doctors and pharmacists can prescribe and dispense alglucosidase alfa. You should be registered in the program and sign documents stating that you understand the risks of using this medicine and the possibility of severe allergic reaction. Ask your doctor or call the drug maker if you have questions about the program or the written requirements.

• Till receiving this medicine, speak your doctor if you have heart malady, lung malady or a breathing mess, or if you are allergic to mice, hamsters, or drug commodity made with "murine" proteins.

• Till every injection, speak your doctor if you have recently been sick with a cool, flu, or another illness.

• Some people receiving an injection of alglucosidase alfa have had a reaction to the infusion. This type of reaction can occur when the medication is injected into the vein, or as long as 3 hours after the injection.

Tell your caregivers or get abnormal medical help right away if you have any signs of a severe allergic reaction, such as feeling restless, nervous, dizzy, numb, tingly, hot or cool, sweaty, nauseated, or lightheaded, or if you have trouble breathing, chest pain or tightness, quick or slow heart course, hives, severe skin rash, seizure (convulsions), or swelling of your person, lips, tongue, or throat.

What is alglucosidase alfa?

Alglucosidase alfa contains an enzyme that naturally occurs in the body in healthy people. Some people lack this enzyme because of a genetic mess. Alglucosidase alfa helps replace this missing enzyme in such people.

Alglucosidase alfa is used to treat a glycogen storage mess called Pompe malady, (also called GAA deficiency) in adults and children who are at least 8 years old.

Alglucosidase alfa may also be used for purposes not listed in this medicine guide.

What must I discuss with my health care provider till receiving alglucosidase alfa?

• You must not receive alglucosidase alfa if you are allergic to it.

• To create certain you can safely use alglucosidase alfa, speak your doctor if you have another medical conditions, especially:

· heart disease;

· lung malady or breathing disorder;

· if you are allergic to mice, hamsters, or drug commodity made with "murine" proteins.

• FDA pregnancy category B. Alglucosidase alfa is not expected to harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant during treatment.

• It is not known whether alglucosidase alfa passes into breast milk or if it could harm a nursing child. Do not receive this medicine without telling your doctor if you are breast-feeding a baby.

• Your name may be listed on the Pompe Registry. This is to track the progress of your malady and the outcome of your treatment with alglucosidase alfa.

How is alglucosidase alfa given?

Alglucosidase alfa is injected into a vein through an IV using an infusion exhaust. You will receive this injection in a clinic or hospital setting. Alglucosidase alfa should be given slowly, and the IV infusion can take up to 4 hours to complete.

• This medicine is generally given once each 2 weeks.

• Till every injection, speak your doctor if you have recently been sick with a cool, flu, or another illness.

• To be certain this medication is helping your condition and is not causing deleterious effects, your blood will need to be tested each 3 months for 2 years and then once each year after that. Visit your doctor regularly.

Alglucosidase alfa is accessible only under a particular program called ACE. Under this program, only registered doctors and pharmacists can prescribe and dispense alglucosidase alfa. You should be registered in the program and sign documents stating that you understand the risks of using this medicine and the possibility of severe allergic reaction. Ask your doctor or call the drug maker if you have questions about the program or the written requirements.

What happens if I miss a dose?

• Call your doctor for instructions if you miss an appointment for your alglucosidase alfa injection.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while receiving alglucosidase alfa?

• Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of alglucosidase alfa?

• Some people receiving an injection of alglucosidase alfa have had a reaction to the infusion. This type of reaction can occur when the medication is injected into the vein, or as long as 3 hours after the injection. Tell your caregivers or get abnormal medical help right away if you have any of these signs of a severe allergic reaction:

· feeling like you might pass out, even while lying down;

· feeling restless, nervous, dizzy, or nauseated;

· pale skin, redness under your skin, sweating, feeling hot or cold;

· quick or slow heart rate;

· pain or tightness in your chest or throat;

· wheezing, trouble breathing;

· cool hands, blue lips;

· back pain;

· numbness, warmth, redness, or tingly feeling;

· seizure (convulsions);

· hives, severe skin rash; or

· swelling of your person, lips, tongue, or throat.

• Call your doctor at once if you have a serious side effect such as:

· pain or fullness in your ear, problems with hearing;

· skin ulcers;

· quick, slow, or uneven heartbeats;

· urinating smaller than normal or not at all;

· weak pulse, fainting, slow breathing (breathing may stop); or

· chest pain or hard feeling, pain spreading to the hand or shoulder, sweating, common ill feeling.

• Smaller serious side effects may include:

· mild skin rash or itching;

· diarrhea, constipation, stomach pain or upset, vomiting;

· sore throat, neck pain;

· pain or swelling in your arms or legs; or

· pain, swelling, burning, or irritation near the IV needle.

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect alglucosidase alfa?

• There may be another drugs that can interact with alglucosidase alfa. Speak your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal commodity. Do not start a new medicine without telling your doctor.

Where can I get more information?

• Your doctor or pharmacist can provide more information about alglucosidase alfa.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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© 2006-2024 medpill.info Last Updated On: 03/09/2024 (0)
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