(a GAL sih daze BAY tah) Brand: Fabrazyme
• Symptoms of allergic or infusion reactions including difficulty breathing; closing of the throat; hives; rash; itching; fever; shaking; chest tightness; tall or low blood pressure; quick heartbeats; muscle pain; stomach pain; nausea or vomiting; dizziness; numbness or tingling; and headache have occurred upon injection of agalsidase beta in much patients. Most patients treated with agalsidase beta develop antibodies to agalsidase beta and much will develop symptoms of an infusion reaction. A slow course of injection of the medicine and pretreatment with another medications may decrease the severity of these symptoms. Abnormal medical attention may be required if a severe allergic reaction is experienced.
• Agalsidase beta is a man-made form of the naturally-occurring enzyme a-galactosidase A. A deficiency of the enzyme a-galactosidase A is called Fabry malady. Agalsidase beta reduces deposits of globotriaosylceramide (GL-3) in the kidneys and another determined another cells in the body.
• Agalsidase beta is used in the treatment of Fabry disease.
• Agalsidase beta may also be used for purposes another than those listed here.
• Till using agalsidase beta, speak your doctor if you have
· had an allergic reaction to agalsidase beta or have antibodies to the medicine; or
· heart problems.
• You may not be able to use agalsidase beta, or you may require a dosage adjustment or particular monitoring during treatment.
• Agalsidase beta is in the FDA pregnancy category B. This means that it is not expected to be deleterious to an unborn child. Do not use agalsidase beta without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether agalsidase beta passes into breast milk. Do not use agalsidase beta without first talking to your doctor if you are breast-feeding a baby.
• Use agalsidase beta exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Agalsidase beta is given by intravenous (into the vein) injection and will most likely be administered by a healthcare provider.
• Your doctor may want you to have blood trials or another medical evaluations during treatment with agalsidase beta to monitor progress and side effects.
• Your healthcare provider will store agalsidase beta as instructed by the manufacturer. If you are storing agalsidase beta at house, your healthcare provider will give you instructions regarding how to store the medication.
• Contact your doctor if you miss a doze of agalsidase beta.
• Contact your doctor, a hospital abnormal room, or a poison control center if an overdose is suspected.
• Although symptoms of an agalsidase beta overdose are not known, an overdose is unlikely to threaten life.
• There are no restrictions on food, beverages, or activity during treatment with agalsidase beta.
• Symptoms of allergic or infusion reactions including difficulty breathing; closing of the throat; hives; rash; itching; fever; shaking; chest tightness; tall or low blood pressure; quick heartbeats; muscle pain; stomach pain; nausea or vomiting; dizziness; numbness or tingling; and headache have occurred upon injection of agalsidase beta in much patients. Most patients treated with agalsidase beta develop antibodies to agalsidase beta and much will develop symptoms of an infusion reaction. A slow course of injection of the medicine and pretreatment with another medications may decrease the severity of these symptoms. Abnormal medical attention may be required if a severe allergic reaction is experienced.
• Side effects another than those listed here may also occur. Conversation to your doctor about any side effect that seems unusual or that is especially bothersome. You may message side effects to FDA at 1-800-FDA-1088.
• Agalsidase beta is not known to interact with another medications. Conversation to your doctor or pharmacist till taking another prescription or over-the-counter medications, including herbal commodity, during treatment with agalsidase beta.
• Your pharmacist has more information about agalsidase beta written for health professionals that you may read.
Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.
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