Acyclovir (Zovirax);
Antiviral; Cap: 200 mg
Inj: 500 mg, 1 gm
Oint: 5% [3, 15 gm]
Susp: 200 mg/5 mL
Tab: 400, 800 mg;
Herpes zoster (immunocompromised): 500 mg/m2/dose PO 4-5 times daily or 1500 mg/m2/day
IV q8h
Herpes zoster (immunocompetent): 80 mg/kg/day PO 5 times daily (max 4000 mg/day) or 30 mg/kg/day
IV q8h
Varicella zoster (chicken pox): 80 mg/kg/day PO qid x 5 days (max 3200 mg/day)
Mucocutaneous HSV infection: 750 mg/m2/day
IV q8h or 15 mg/kg/day
IV q8h x 7 days.
Genital herpes or HSV (immunocompromised): 80 mg/kg/day PO 3-5 times daily (max 1000 mg/day)
Herpes encephalitis:
birth-12 yrs: 60 mg/kg/day
IV q8h
>12 yrs: 30 mg/kg/day
IV q8h
Infuse each
IV dose over 1 hour. Adjust in
renal impairment. Patients should be well hydrated to avoid urolithiasis.
Topical: Apply to affected area q3h while awake for 7 days. avoid