ACITRETIN AND CONTRACEPTIVES

There seems to be no evidence that the reliability of the combined oral contraceptives is affected by acitretin, and they are the contraceptive method of choice with teratogenic drugs. Progestogen-only oral contraceptives are not generally considered reliable enough for use with teratogenic drugs.
Contraceptives should be started one month before acitretin and continued for 2 years after stopping acitretin. In the USA, it is standard practice to recommend that a second form of contraception, such as a barrier method, should also be used. This is because, even though hormonal methods of contraception are highly effective, they do, on rare occasions, fail.
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